A monitoring agent that wakes on its own schedule desynchronises the whole machine.
Tightly-coupled jobs advance in lockstep through collective operations, an MPI_Allreduce or a barrier, and the slowest rank gates every other one. A host agent that steals a few microseconds on a single node, on its own cadence rather than the application's, ripples into idle time across thousands of ranks. The effect is worse at scale, not better: the per-node noise stays constant while the cost of staying synchronised grows. This is the OS-jitter problem the field has measured since the early 2000s, and it is the first reason you cannot simply push the enterprise endpoint agent down to every compute node.
Petrini, Kerbyson & Pakin, “The Case of the Missing Supercomputer Performance”, SC 2003.